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June 11, 2025publication

StabLyzeGraph published in Protein Science

Co-developed with the Cosconati Lab, StabLyzeGraph predicts stabilising mutations from sequence and structural context.

A peer-reviewed description of StabLyzeGraph, Abilita's internal graph-based predictor for mutations that stabilise multi-span membrane proteins, was published in Protein Science. The tool was co-developed with the Cosconati Lab and is integrated into the EMP™ discovery loop — ranking candidate variants generated by directed evolution before they ever reach the bench.

Abilita Therapeutics

Drugging multi-span membrane proteins through directed evolution and AI-guided design. San Diego, California.

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